Probes labelled with energy transfer coupled dyes
Patent
·
OSTI ID:563688
Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids. 7 figs.
- Research Organization:
- University of California
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG03-91ER61125
- Assignee:
- Univ. of California, Oakland, CA (United States)
- Patent Number(s):
- US 5,688,648/A/
- Application Number:
- PAN: 8-574,890
- OSTI ID:
- 563688
- Country of Publication:
- United States
- Language:
- English
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