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Title: Probes labelled with energy transfer coupled dyes

Patent ·
OSTI ID:563688

Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids. 7 figs.

Research Organization:
Univ. of California (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
FG03-91ER61125
Assignee:
Univ. of California, Oakland, CA (United States)
Patent Number(s):
US 5,688,648/A/
Application Number:
PAN: 8-574,890
OSTI ID:
563688
Resource Relation:
Other Information: PBD: 18 Nov 1997
Country of Publication:
United States
Language:
English