Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels
Patent
·
OSTI ID:321188
Cyanine dyes are used as the donor fluorophore in energy transfer labels in which light energy is absorbed by a donor fluorophore and transferred to an acceptor fluorophore which responds to the transfer by emitting fluorescent light for detection. The cyanine dyes impart an unusually high sensitivity to the labels thereby improving their usefulness in a wide variety of biochemical procedures, particularly nucleic acid sequencing, nucleic acid fragment sizing, and related procedures. 22 figs.
- Research Organization:
- Univ. of California (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG03-91ER61125
- Assignee:
- Univ. of California, Oakland, CA (United States)
- Patent Number(s):
- US 5,853,992/A/
- Application Number:
- PAN: 8-726,178
- OSTI ID:
- 321188
- Resource Relation:
- Other Information: PBD: 29 Dec 1998
- Country of Publication:
- United States
- Language:
- English
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