Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Radioprotective properties of etioporphyrin-1 derivatives in gamma-irradiated mice

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5590387
The radioprotective properties of eight derivatives of etioporphyrin-1 were studied on C57B1/6 mice. It was demonstrated that mesodimethyl-aminoethyl-etioporphyrin-1 has a wide range of radioprotective action and prolonged effect when given preventively. Results are submitted on the modifying effect of this compound on survival of mice exposed to acute ..gamma..-radiation (900 R), kinetics of postradiation changes in bone marrow, permeability of cell membranes, mitotic activity of intestinal epithelial cells and protein synthesis.
OSTI ID:
5590387
Report Number(s):
DOE-tr-4/12
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 18:6; ISSN RADBA
Country of Publication:
United States
Language:
English