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Recessive lethal mutations and their role in radiation inactivation of cells: experiments on yeast organisms. [. gamma. rays; Saccharomyces strains]

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5458187
; ;
The yield of lesions determining unviability of ascospores of irradiated yeast diploid cells is about 1/40th of the yield of lesions that cause death of irradiated haploid cells (per unit radiation dose per genome). Such lesions are more often encountered in clones formed from irradiated cells, in which are inherent genetic instability and irregularity of segregation of genetic markers; viable ascospores formed by cells of such clones, in turn, often originate unstable clones. It may be assumed that a significant share of lesions causing unviability of ascospores of irradiated cells does not appear during irradiation, but in the course of subsequent disturbances of mitosis and/or meiosis; in some cases, such injuries consist of loss of some chromosomes. Thus, recessive lethal mutations, in the classical meaning of this term, do not play a substantial role in radiation inactivation, not only of diploid cells, but haploids.
OSTI ID:
5458187
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 18:4; ISSN RADBA
Country of Publication:
United States
Language:
English

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Related Subjects

560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL ISOTOPES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CESIUM 137
CESIUM ISOTOPES
COBALT 60
COBALT ISOTOPES
CORRELATIONS
DATA
DATA FORMS
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
EXPERIMENTAL DATA
FUNGI
GAMMA RADIATION
GENETIC EFFECTS
GENETIC RADIATION EFFECTS
GRAPHS
INACTIVATION
INFORMATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOLATED VALUES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LETHAL MUTATIONS
MICROORGANISMS
MINUTES LIVING RADIOISOTOPES
MUTATION FREQUENCY
MUTATIONS
NUCLEI
NUMERICAL DATA
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
PLANTS
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOISOTOPES
RECESSIVE MUTATIONS
SACCHAROMYCES
SACCHAROMYCES CEREVISIAE
SPORES
SURVIVAL CURVES
YEARS LIVING RADIOISOTOPES
YEASTS