Comparison between health effects of cadmium and cadmium concentration in urine among inhabitants of the Itai-Itai disease endemic district

Journal Article · Sat Mar 31 23:00:00 EST 1979 · Environ. Res.; (United States)

DOI:https://doi.org/10.1016/0013-9351(79)90116-6· OSTI ID:5456638

Nogawa, K; Ishizaki, A; Kobayashi, E

The relationship between urinary cadmium concentration (micrograms/g creatinine) and the health effects of cadmium exposure was studied in 406 inhabitants who lived in and around the Jinzu River basin. Cadmium concentration in urine was employed as the index of cadmium exposure. Total protein, glucose, calcium, and phosphorus in urine and calcium, inorganic phosphorus, and alkaline phosphatase in serum served as indices of health effects. On a group basis a close relationship was found between cadmium concentration in urine and health effects. Prevalence rates of indices of health effects increased proportionally with increasing cadmium concentrations in urine. It was concluded that cadmium concentration in urine expressed as micrograms/g creatinine is a useful parameter in estimating the health effects of cadmium exposure from the environment.

• Research Organization: Kanazawa Medical Univ., Ishikawaken, Japan
• OSTI ID: 5456638
• Journal Information: Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 18:2; ISSN ENVRA
• Country of Publication: United States
• Language: English

Related Subjects

551000 -- Physiological Systems
552000 -- Public Health
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
ALDEHYDES
ASIA
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY
BODY FLUIDS
CADMIUM
CARBOHYDRATES
CHEMICAL ANALYSIS
DATA
DATA FORMS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
ELEMENTS
ENZYMES
EPIDEMIOLOGY
EXPERIMENTAL DATA
GLUCOSE
HEXOSES
HUMAN POPULATIONS
INFORMATION
INORGANIC PHOSPHORS
ISOLATED VALUES
JAPAN
KIDNEYS
MATERIALS
MEDICAL SURVEILLANCE
METALS
MONOSACCHARIDES
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANS
PHOSPHORS
PHOSPHOTRANSFERASES
POPULATIONS
PROTEINS
QUANTITATIVE CHEMICAL ANALYSIS
QUANTITY RATIO
RHEUMATIC DISEASES
SACCHARIDES
SKELETAL DISEASES
SKELETON
TOXICITY
TRANSFERASES
URINE
WASTES