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Relationship between the renal effects of cadmium and cadmium concentration in urine amoung the inhabitants of cadmium-polluted areas

Journal Article · · Environ. Res.; (United States)
OSTI ID:5204100
; ; ;

The relationship between urinary cadmium concentration and the effects of cadmium on the kidney was studied in inhabitants of cadmium-polluted areas. As the indexes of the effects of cadmium on the kidney, total protein, retinol-binding protein, glucose, ..cap alpha..-amino N, and proline in urine were employed. The prevalence of proteinuria, glucosuria, proteinuria with glucosuria, tubular proteinuria, and aminoaciduria increased distinctly with increasing cadmium in urine when the inhabitants were sorted according to their urinary cadmium concentrations expressed as micrograms per gram of creatinine. Probit analysis of urinary cadmium concentration (micrograms per gram of creatinine) and prevalence of renal effects showed linear regression lines. Therefore, cadmium concentration in urine expressed as micrograms per gram of creatinine seems to be useful in estimating the renal effects of cadmium exposure in the environment.

Research Organization:
Kanazawa Medical Univ., Ishikawa-ken, Japan
OSTI ID:
5204100
Journal Information:
Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 14:3; ISSN ENVRA
Country of Publication:
United States
Language:
English

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Related Subjects

550900 -- Pathology
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALDEHYDES
AMINES
AMINO ACIDS
ANIMALS
ASIA
AZOLES
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY
BODY FLUIDS
CADMIUM
CARBOHYDRATES
CARBOXYLIC ACIDS
CRYOGENIC FLUIDS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
ELEMENTS
FLUIDS
GLUCOSE
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
HEXOSES
JAPAN
KIDNEYS
MAMMALS
MAN
METALS
MONOSACCHARIDES
NITROGEN
NONMETALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
POLLUTION
PRIMATES
PROLINE
PROTEINS
PYRROLES
PYRROLIDINES
QUANTITY RATIO
SACCHARIDES
URINE
VERTEBRATES
WASTES