Study of the relationship between cadmium concentrations in urine and renal effects of cadmium
The relationship between urinary cadmium concentration expressed as microgram/g creatinine and renal effects of cadmium exposure was studied in 542 inhabitants over 20 years of age who lived in the Jinzu River basin which is polluted by cadmium. Cadmium concentration in urine was employed as the index of cadmium exposure. Total protein with glucose, beta 2-microglobulin, retinol binding protein, and proline served as indices of renal effects. The prevalent rate of high beta 2-microglobulin excretion was the highest among these indices both in men and women. Prevalence rates of indices of renal effects increased proportionally with increasing cadmium concentrations in urine and probit linear regression lines could be calculated between them. This method may be useful for evaluating the risk of renal damage of exposed inhabitants.
- Research Organization:
- Kanazawa Medical Univ., Ishikawa-ken, Japan
- OSTI ID:
- 6671544
- Journal Information:
- Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 28; ISSN EVHPA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
AMINO ACIDS
AZOLES
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY
BODY FLUIDS
CADMIUM
CARBOHYDRATES
CARBOXYLIC ACIDS
CREATININE
ELEMENTS
ENVIRONMENTAL EXPOSURE PATHWAY
GLOBULINS
GLUCOPROTEINS
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
HUMAN POPULATIONS
IMIDAZOLES
IMINES
KIDNEYS
MATERIALS
METALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
POPULATIONS
PROLINE
PROTEINS
PYRROLES
PYRROLIDINES
QUANTITY RATIO
SACCHARIDES
URINE
WASTES