Effect of zinc ions on the actions of prolactin on RNA and casein syntheses in mouse mammary gland explants

Journal Article · Sat Dec 01 04:00:00 EST 1979 · Proc. Soc. Exp. Biol. Med.; (United States)

DOI:https://doi.org/10.3181/00379727-162-40705· OSTI ID:5432180

Rillema, J A

Zinc ions, at concentrations which were shown to inhibit guanylate cyclase activity, abolished the actions of prolactin on RNA and casein synthesis in cultured mouse mammary gland explants. These observations are compatible with the hypothesis that certain of the actions of prolactin in the mammary gland may be mediated by cyclic GMP.

• Research Organization: Wayne State Univ., Detroit, MI
• OSTI ID: 5432180
• Journal Information: Proc. Soc. Exp. Biol. Med.; (United States), Journal Name: Proc. Soc. Exp. Biol. Med.; (United States) Vol. 162:3; ISSN PSEBA
• Country of Publication: United States
• Language: English

Related Subjects

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560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOSYNTHESIS
BODY
CASEIN
CELL CULTURES
COMPARATIVE EVALUATIONS
DATA
DATA FORMS
DOSE-RESPONSE RELATIONSHIPS
ELEMENTS
ENZYME INHIBITORS
EXPERIMENTAL DATA
GLANDS
GONADOTROPINS
GUANOSINE
HETEROCYCLIC COMPOUNDS
HORMONES
HYDROGEN ISOTOPES
INFORMATION
ISOLATED VALUES
ISOTOPES
LABELLED COMPOUNDS
LIGHT NUCLEI
LTH
MAMMALS
MAMMARY GLANDS
METALS
MICE
NUCLEI
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
NUMERICAL DATA
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
PEPTIDE HORMONES
PITUITARY HORMONES
PROTEINS
PURINES
RADIOISOTOPES
RESPONSE MODIFYING FACTORS
RIBOSIDES
RNA
RODENTS
SENSITIVITY
SYNTHESIS
TOXICITY
TRITIUM
VERTEBRATES
YEARS LIVING RADIOISOTOPES
ZINC