Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae. [X radiation, uv radiation]
Journal Article
·
· Genetics; (United States)
OSTI ID:5237279
Methyl methanesulfonate (MMS)-sensitive mutants of Saccharomyces cerevisiae belonging to four different complementation groups, when homozygous, increase the rate of spontaneous mitotic segregation to canavanine resistance from heterozygous sensitive (can/sup r//+) diploids by 13- to 170-fold. The mms8-1 mutant is MMS and x-ray sensitive and increases the rate of spontaneous mitotic segregation 170-fold. The mms9-1 and mms13-1 mutants are sensitive to x rays and uv, respectively, in addition to MMS, and increase the rate of spontaneous mitotic segregation by 13-fold and 85-fold, respectively. The mutant mms21-1 is sensitive to MMS, x rays and uv and increases the rate of spontaneous mitotic segregation 23-fold.
- Research Organization:
- Univ. of Rochester, NY
- OSTI ID:
- 5237279
- Journal Information:
- Genetics; (United States), Journal Name: Genetics; (United States) Vol. 87:2; ISSN GENTA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOMASS
CELL DIVISION
ELECTROMAGNETIC RADIATION
ENERGY SOURCES
ESTERS
FUNGI
IONIZING RADIATIONS
METHYL METHANESULFONATE
MICROORGANISMS
MITOSIS
MUTAGENS
MUTANTS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PLANTS
RADIATION EFFECTS
RADIATIONS
RENEWABLE ENERGY SOURCES
SACCHAROMYCES
SACCHAROMYCES CEREVISIAE
SULFONIC ACID ESTERS
ULTRAVIOLET RADIATION
X RADIATION
YEASTS
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOMASS
CELL DIVISION
ELECTROMAGNETIC RADIATION
ENERGY SOURCES
ESTERS
FUNGI
IONIZING RADIATIONS
METHYL METHANESULFONATE
MICROORGANISMS
MITOSIS
MUTAGENS
MUTANTS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PLANTS
RADIATION EFFECTS
RADIATIONS
RENEWABLE ENERGY SOURCES
SACCHAROMYCES
SACCHAROMYCES CEREVISIAE
SULFONIC ACID ESTERS
ULTRAVIOLET RADIATION
X RADIATION
YEASTS