STUDIES ON THE COMBINED EFFECTS OF RADIATION AND VARIOUS CHEMICALS ON THE MITOTIC CELLS. XVIII. EFFECTS OF THE COMBINED USE OF CHLORPROMAZINE AND X-RAYS

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Nippon Igaku Hoshasen Gakkai Zasshi (Japan)

OSTI ID:4839266

Genma, M

An experimental study was made on the root tip of the bean (Vicia faba) and MTK sarcoma III. The radiation effects were observed as 3 phenomena: the frequency of mitosis, the difference of each mitotic phase in number, and the frequency of abnormality of chromosomes during metaphase. The effect of chlorpromazine as a protective agent against lethal effects by radiation on the mouse are summarized as follows: Chlorpromazine as well as x rays caused a decrease in number of mitotic cells of the root tip of bean; Injection of the drug before x radiation showed a much stronger effect on the root tip, in decreasing its mitotic cells, than the effect of either the drug or x radiation alone. (Abstr. Japan Med., 1: No. 10, 1961).

• Research Organization: Hokkaido Univ. School of Medicine, Sapporo, Japan
• NSA Number: NSA-15-027453
• OSTI ID: 4839266
• Journal Information: Nippon Igaku Hoshasen Gakkai Zasshi (Japan), Journal Name: Nippon Igaku Hoshasen Gakkai Zasshi (Japan) Vol. Vol: 19; ISSN NHGZA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
CHEMICALS
CHLORPROMAZINE
CHROMOSOMES
MICE
MITOSIS
PLANT CELLS
RADIATION EFFECTS
RADIATION PROTECTION
ROOTS
X RADIATION