Plutonium Inhalation Studies: IV. Mortality in Dogs after Inhalation of Pu 239 O 2
Twenty-eight beagle dogs deposited 1 to 130 mu c of plutonium dioxide by inhalation. Two dogs were alive 21 months after exposure. All deaths occurred 2 to 14 months after exposure and were due to respiratory insufficiency. Lungs contained 95% and the bronchial lymph nodes 4% of the total plutonium content. Clinical symptoms included increased respiratory rates, 20% weight loss, and marked lymphopenia. Histopathologic effects were confined to lungs and bronchial lymph nodes. It was concluded that initial deposition of O.1 mu c of Pu/sup 239/ per gram of lung would rarely cause death of a dog within a year. (auth)
- Research Organization:
- Hanford Atomic Products Operation, Richland, Wash.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-16-021886
- OSTI ID:
- 4838139
- Journal Information:
- Radiation Research, Journal Name: Radiation Research Journal Issue: 6 Vol. 16; ISSN 0033-7587
- Publisher:
- Radiation Research Society
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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