PLUTONIUM INHALATION STUDIES. IV. MORTALITY IN DOGS AFTER INHALATION OF Pu$sup 239$$O$$sub 2$

Technical Report · Wed Mar 01 04:00:00 EST 1961

OSTI ID:4024566

Bair, W J; Willard, D H

In 28 beagle dogs depositing 1 to 130 mu c of plutonium dioxide by inhalation, deaths due to respiratory insufficiency occurred two months to a year after exposure. Lungs contained 95% and the bronchial lymph nodes 4% of the total plutonium content. Clinical symptoms included increased respiratory rates, 20% weight loss and marked lymphopenia. Histopathologic effects were confined to lungs and bronchial lymph nodes. It was concluded that initial deposition of 0.1 mu c Pu/sup 239/ per gram of lung would rarely cause death of a dog within a year. (auth)

• Research Organization: General Electric Co. Hanford Atomic Products Operation, Richland, Wash.
• DOE Contract Number: AT(45-1)-1350
• NSA Number: NSA-15-024658
• OSTI ID: 4024566
• Report Number(s): HW-68803
• Country of Publication: United States
• Language: English

Related Subjects

ANIMALS
BIOLOGY AND MEDICINE
DOGS
LIFETIME
LUNGS
LYMPH NODES
LYMPH SYSTEM
LYMPHOCYTES
PLUTONIUM 239
PLUTONIUM OXIDES
QUANTITY RATIO