METABOLISM OF ZINC-65 IN THE RAT. CONSIDERATION OF PERMISSIBLE EXPOSURE LIMITS

Journal Article · Tue Aug 01 04:00:00 EDT 1961 · Health Physics (England)

DOI:https://doi.org/10.1097/00004032-196107000-00002· OSTI ID:4834649

Ballou, J E; Thompson, R C

Data are presented on the absorption of Zn/sup 65/ under various conditions, on its distribution and retention following a single administration, and on its buildup in tissues during chronic feeding. Highest concentrations of Zn/sup 65/ were observed in hair, bone, and prostate, the three tissues which did not attain steady-state levels of Zn/sup 65/ during extended periods of Zn/sup 65/ feeding. Accumulation in the total-body appears to be the critical consideration, however, due to the greater absorption of the decay energy in the larger organism and the lower permissible dose rate recommended for total body irradiation. Special consideration may need be given to the very young, in view of the ready transfer ot Zn/sup 65/ across the placenta and the enhanced intestinal absorption during the first few weeks of life. (auth)

• Research Organization: General Electric Co., Richland, Wash.
• Sponsoring Organization: USDOE
• NSA Number: NSA-15-030397
• OSTI ID: 4834649
• Report Number(s): HW-SA-2020; 0017-9078
• Journal Information: Health Physics (England), Journal Name: Health Physics (England) Vol. Vol: 6; ISSN HLTPA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ABSORPTION
BIOLOGY AND MEDICINE
BONES
DECAY
ENERGY
FOOD
GLANDS
HAIR
INTESTINE
METABOLISM
PLACENTA
PROSTATE
QUANTITY RATIO
RADIATION DOSES
RATS
TISSUES
ZINC 65