THE ACTION OF GONADS ON THE CONCENTRATION OF RADIO-IODINE BY THE SUBMAXILLARY GLAND OF C$sub 3$H MICE

Journal Article · Thu Mar 01 04:00:00 EST 1962 · Revue Canadienne de Biologie (Canada)

OSTI ID:4827709

Llach, J L; Tramezzani, J H

The I/sup 131/ submaxillary/I/sup 131/ blood ratio of normal C/sub 3/H male mice, receiving doses of 5 mu c, is higher than the submaxillary/blood ratio of normal C/sub 3/H female mice. This sexual difference does not disappear after castration. The male castrated mice show a higher submaxillary/blood ratio than normal animals and no modification is observed in castrated females. Thus the sexual difference is more evident in castrated animals. Testosterone propionate, at doses of 10 mu g or 20 mu g during 14 and 13 days, respectively, restores in the male mice the changes produced by castration. Estradiol benzoate administered to the castrated female at doses of 0.5 mu g and 5 mu g during 6 and 7 days, respectively, decreases the submaxillary/blood ratio in relation to the given dose. (auth)

• Research Organization: Instituto de Biologia y Medicina Experimental, Buenos Aires
• NSA Number: NSA-16-021887
• OSTI ID: 4827709
• Journal Information: Revue Canadienne de Biologie (Canada), Journal Name: Revue Canadienne de Biologie (Canada) Vol. Vol: 21: No. 1; ISSN RCBIA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BLOOD
ESTRADIOL
GLANDS
GONADS
HORMONES
IODINE 131
MICE
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
SALIVARY GLANDS
SEX
SURGERY
TESTOSTERONE
TRACER TECHNIQUES