SOME PROBLEMS IN THE CULTURING AND RADIATION SENSITIVITY OF NORMAL HUMAN CELLS
Journal Article
·
· Exptl. Cell Research
Cells of normal human kidney, lung, and skin tissues were cultured for several months in media containing either fetal calf or human plus horse sera. Fibroblastic cells became predominant in all cultures. In kidney cultures epitheliallike cells also were present but always in association with fibroblasts. The x-radiation sensitivities observed by single cell colony formation ranged from 41 to 480 rads for 37 per cent survival. Individual cultures shifted their sensitivities widely with time and with changes in the epithelial to fibroblast ratio. Chromosome studies indicated constancy of the normal karyotype during the culture period. Radiation produced typical aberrations. (auth)
- Research Organization:
- Charles F. Kettering Foundation, Yellow Springs, Ohio
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-16-026797
- OSTI ID:
- 4821389
- Journal Information:
- Exptl. Cell Research, Journal Name: Exptl. Cell Research Vol. Vol: 27
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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