Neutron Activation Paper Chromatographic Analysis of Phospholipids in Human Liver and Bile

Journal Article · Sun Jan 01 04:00:00 EST 1961 · Acta Chemica Scandinavica (1989)

DOI:https://doi.org/10.3891/acta.chem.scand.15-1595· OSTI ID:4811762

Nakayama, Fumio; Blomstrand, Rolf; Sillén, Lars Gunnar

Phospholtptds in human liver and bile were analyzed using a neutron activation paper chromatographic technique. Phosphatidylserine, phosphoinositide, and choline plasmalogen as well as lecithin, phosphatidylethanolamine, and sphingomyelin were found to be present. Further evidence for the presence of lysolecithin in normal human bile is also presented. Similar results were obtained with rat bile using radioactive phosphorus. Lecithin comprises more than 80% of the phospholipids in human bile in contrast to liver, where it comprises 45%, indicating a selective secretion of phospholipid classes from liver into bile. The difference found in the fatty acid composition of the total phospholipids in human liver and bile by gas chromatography, coincides with the findings on the differences in phospholipid composition.

• Research Organization: Univ. of Lund, Sweden
• Sponsoring Organization: USDOE
• NSA Number: NSA-16-007489
• OSTI ID: 4811762
• Journal Information: Acta Chemica Scandinavica (1989), Journal Name: Acta Chemica Scandinavica (1989) Vol. 15; ISSN 0904-213X; ISSN acsaa4
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ACTIVATION ANALYSIS
CHEMISTRY
CHROMATOGRAPHY
LIPIDS
LIVER
MAN
NEUTRONS
PAPER
PHOSPHOLIPIDS