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Effect of sodium citrate on the breakdown of deoxyribonucleic Acid of escherichia freundii induced by padiation

Journal Article · · Naturwissenschaften
DOI:https://doi.org/10.1007/BF00628024· OSTI ID:4805051
The radioinduced breakdown of desoxyribonucleic acid (DNA) was investigated on Escherichia freundii grown to the stationary phase in a mineral medium containing glucose as a sole organic substance. Bacteria suspended in distilled water and irradiated show an early breakdown of the DNA that continues during incubation. High concentrations of sodium citrate inhibits this breakdown but low con centrations increase the breakdown. The addition of calcium chloride and magnesium sulfate to low concentrations of sodium citrate decreases the accelerating effect. Various hypotheses on the mechanism of radioinduced breakdown are discussed in the light of the sodium citrate effect. (J.S.R.)
Research Organization:
Universite, Liege
Sponsoring Organization:
USDOE
NSA Number:
NSA-16-026815
OSTI ID:
4805051
Journal Information:
Naturwissenschaften, Journal Name: Naturwissenschaften Journal Issue: 10 Vol. 49; ISSN 0028-1042
Country of Publication:
Country unknown/Code not available
Language:
English