STUDY ON THE RADIATION PROTECTIVE EFFECT OF RUTIN IN WHOLEBODY IRRADIATION OF WHITE MICE (in German)
>Experimental investigations done in 105 white mice of a heterozygous breed showed that rutin has a radiation protection effect when administered after 600 r of wholebody irradiation. A mechanism unknown in the past is assumed, because the radiation protection substances published previously have shown a protection effect only if given before irradiation. It is assumed, that the effect of rutin is caused, mainly, by a sealing of vessels and membranes. The mean survival time was 9 days for the animal group irradiated with x rays only. It could be increased up to 24 days by additional administration of 5 mg rutin over a period of 10 days. At the same time the average body weight did not decrease at the same rate as that of the animals irradiated only. (auth)
- Research Organization:
- Medizinische Universitatsklinik, Erlangen/Nurnberg, Ger.; Universitat, Giessen, Ger.
- NSA Number:
- NSA-16-014601
- OSTI ID:
- 4798447
- Journal Information:
- Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 117; ISSN STRAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- German
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