STUDY ON A BIOLOGICAL RADIATION PROTECTION. XLV. ACTION OF RADIATION PROTECTION SUBSTANCES ON THE RADIATION DAMAGE OF BONE MORROW, SPLEEN, AND THYMUS (in German)
The reaction of thymus, spleen, and bone marrow of mice, treated with the radiation protective substances 5-hydroxytryptamine (serotonin) or cysteamine before an x-ray irradiation is investigated and compared with untreated, irradiated animals, The radiation injury in spleen and thymu; is, in both groups, the same during the first few days. Later, only the protected animals show a faster recovery of the organs. A protection effect in the bone marrow can be seen to occur immediately after irradiation. The decrease of the cell counts in the marrow is less significant in the treated animals; the protection factor is about 2. It is probable, that only a few cells in the bone marrow are protected against the radiation injury by the protection substances. However, the direct proof of the existence of those cells still has to be established. (auth)
- Research Organization:
- Universitat, Freiburg i. B.; and Heiligenberg-Instituts, Ger.
- NSA Number:
- NSA-16-016299
- OSTI ID:
- 4782432
- Journal Information:
- Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 117; ISSN STRAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- German
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