A STUDY OF RADIOSENSITIVE AND RADIORESISTANT MUTANTS OF ESCHERICHIA COLI STRAIN B

Journal Article · Sun Jan 01 04:00:00 EST 1961 · Journal of General Microbiology (England)

DOI:https://doi.org/10.1099/00221287-24-1-1· OSTI ID:4792368

Hill, R F; Simson, E

Relative differences in radiosensitivity between Escherichia coli strain B and the mutant strains, B/r (more resistant than B) and two types of B/sub s/ (more sensitive), are maintained with respect to inactivation by ultraviolet radiation, x rays, and decay of incorporated P/sup 32/. The differences cannot be ascribed to variations in number of nuclei or in content of DNA or RNA. The effectiveness of various post-irradiation and post-decay treatments in preventing inactivation varies for each strain. With the exception of reactivation by light, strain B/r is less reactivable than B and B/sub s/. The strains do not differ in their rates of mutation to resistance to bacteriophage T/sub s/. However, the rates of mutation of the B/sub s/ mutants to the first step of furacinresistance are considerably lower than the rate for the parent strain B. From one of the B/sub s/ mutants, new strains were obtained whose properties are mixtures of those of B and B/r. (auth)

• Research Organization: Columbia Univ., New York
• Sponsoring Organization: USDOE
• NSA Number: NSA-16-016206
• OSTI ID: 4792368
• Journal Information: Journal of General Microbiology (England), Journal Name: Journal of General Microbiology (England) Vol. Vol: 24; ISSN JGMIA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BACTERIA
BACTERIOPHAGES
BIOLOGY AND MEDICINE
DECAY
MUTATIONS
NUCLEIC ACIDS
PHOSPHORUS 32
QUANTITY RATIO
RADIOSENSITIVITY
RIBONUCLEIC ACID
ULTRAVIOLET RADIATION
X RADIATION