RADIORESISTANT MUTANTS OF ESCHERICHIA COLI B (ORNL)

Journal Article · Fri Nov 01 04:00:00 EST 1963 · Radiation Res.

DOI:https://doi.org/10.2307/3571367· OSTI ID:4162601

Greenberg, J; Woody-Karrer, P

Radio-resistant mutants of E. coli B (ORNL) were isolated from among survivors of treatment with uv radiation and with 1-methyl-3-nitro-1- nitrosoguanidine. The mutants surviving uv irradiation were equally resistant to uv and x radiation but could be differentiated into four classes on the basis of their cross-resistance to radiomimetic chemicals. Two of these classes also represented all the radioresistant mutants isolated after 1-methyl-3-nitro- 1nitrosoguanidine treatment. The radioresistant mutants of B (ORNL) diifer from those isolated earlier by other investigators. They all also differ from the radioresistant mutants isolated from E. coli S, a variant of strain B. An explanation for the observed differences among radioresistant strains of B isolated at different times is presented. (auth)

• Research Organization: Palo Alto Medical Research Foundation, Calif.
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-001420
• OSTI ID: 4162601
• Journal Information: Radiation Res., Journal Name: Radiation Res. Vol. Vol: 20
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BACTERIA
BIOLOGY AND MEDICINE
CHEMICALS
ESCHERICHIA COLI
GUANIDINE
MUTATIONS
NUCLEIC ACIDS
RADIATION EFFECTS
RADIOSENSITIVITY
ULTRAVIOLET RADIATION
VARIATIONS
X RADIATION