RESISTANCE AND CROSS-RESISTANCE OF ESCHERICHIA COLI MUTANTS TO ANTICANCER AGENTS. NITROGEN MUSTARD AND NITROMIN
The cross-resistance relationships among seven mutants of E. coli strain S selected for resistance to nitrogen mustard and nitromin are described. The data for two first-step nitromin-resistant mutants to seven radiomimetic chemicals, ultraviolet light, 6-diazo-5-oxo-L-norleucine, and penicillin are presented. Three qualitatively different radioresistant mutations were established on the basis of the cross-resistance to ultraviolet light and, hence, would be indistinguishable by this criterion alone. (auth)
- Research Organization:
- Stanford Research Inst., Menlo Park, Calif.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-028973
- OSTI ID:
- 4843141
- Journal Information:
- Radiation Research, Journal Name: Radiation Research Vol. Vol: 15
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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