BIOCHEMICAL MUTATION INDUCED IN TORULOPSIS UTILIS BY IONIZING RADIATIONS

Journal Article · Mon Jan 01 04:00:00 EST 1962 · Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.)

OSTI ID:4785916

Sokurova, E N; Volkova, T M

The causes of biochemnical mutations in microorganisns are of a great interest because the mutants contain injured cells in a well-defined portion of the biosynthesis chain of a given compound. This problem was studied in the yeast cells Torulopsis utilis in aqueous suspension which were exposed to the gamma radiation of a 55 r/sec Co/sup 60/ source, determining the appearance of mutants in the original, normal cells and in those formed after irradiation and deficient in biofin. It was found thaf irradiation increases the frequency of biochemical mutations as compared with spontaneous mutations. The frequency of biochemical mutations increases in direct proportion with the exposure; this linear correlation was more marked in the case of the biotindepleted strain. No linearity could be established between the dose and the number of cells with a slowed-down growth rate. Some of the slowly growing mutants exhibited injuries to their cytochromes, ofhers to the cell division mechanism. The frequency of the various biochemical mutations was not the same: mutations depleted in biotin and B/sub 1/ content occurred most frequently. (TTT)

• Research Organization: Inst. of Microbiology, Academy of Sciences, USSR
• NSA Number: NSA-16-030256
• OSTI ID: 4785916
• Journal Information: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Journal Name: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.) Vol. Vol: 2; ISSN RADOA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

BIOCHEMISTRY
BIOLOGY AND MEDICINE
COBALT 60
FUNGI
GAMMA RADIATION
GENETICS
MUTATIONS
QUANTITY RATIO
RADIATION EFFECTS
SUSPENSIONS
TORULOPSIS
VITAMIN B-1
VITAMIN H
VITAMINS
WATER
YEASTS