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SYNTHESIS OF CARBON-14 LABELED DEOXYRIBONUCLEOSIDES

Journal Article · · Canadian Journal of Chemistry (Canada)
DOI:https://doi.org/10.1139/v62-267· OSTI ID:4785530
The enzymatic tiansfer of deoxyribose from a purine or a pyrimldine deoxyriboside to a carbon-l4-labeled purine or pyrimidine base affords an efficient means of preparing labeled deoxyribonucleosides. Deoxyadenosine-8-C/ sup 14/, hymidine2-C/sup 14/, with the natuial BETA -configuration, were prepared in good yields and isolated in radiochemically pure form by large-scale paper chromatography. (auth)
Research Organization:
Los Alamos Scientific Lab., N. Mex.
Sponsoring Organization:
USDOE
NSA Number:
NSA-16-030313
OSTI ID:
4785530
Report Number(s):
LADC-5345; 0008-4042
Journal Information:
Canadian Journal of Chemistry (Canada), Journal Name: Canadian Journal of Chemistry (Canada) Vol. Vol: 40; ISSN CJCHA
Country of Publication:
United States
Language:
English

References (7)

2-Deoxy-D-ribose. IV. A Direct Synthesis of 2'-Deoxyadenosine and its Anomer through 2-Deoxy-D-ribose Derivatives2 journal July 1960
Purification and Properties of Trans-N-Deoxyribosylase journal August 1958
Desoxyribose-1-Phosphate journal June 1950
Isolation and Properties of an O-Acetyl-4-O-methylglucurono-xyloglycan from the Wood of White Birch (Betula papyrifera)1 journal October 1960
The Enzymatic Synthesis of Nucleosides journal March 1954
Protein Measurement with the Folin Phenol Reagent journal November 1951
The Enzymatic Synthesis of Purine Ribosides journal February 1947

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