Intestinal Transport of Selenium-75 Selenomethionine
When measured simultaneously, selenium-75 selenomethionine accumulated identically with sulfur-35 methionine across everted hamster intestinal sacs in the presence of carrier methionine. The apparent Km for L-methionine transport was 0.8 x 10-3 M, as calculated from the beta emissions of S35-methionine or the gamma emissions of Se75-selenomethionine. Absorption of Se75-selenomethionine from the gastrointestinal tract of man also occurred, with pesk blood levels being reached in about 3 hours. Because of the 122-day half life of selenium-75 and lts multiple gamma emissions, Se75- selenomethionine may serve as a tool in evaluating amino-acid absorption.
- Research Organization:
- Univ. of Buffalo School of Medicine
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-16-014445
- OSTI ID:
- 4785358
- Journal Information:
- Science, Journal Name: Science Journal Issue: 3511 Vol. 136; ISSN 0036-8075
- Publisher:
- AAAS
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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