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EFFECT OF RADIATION ON UREASE

Journal Article · · J. Albert Einstein Med. Center
OSTI ID:4770778
S>Solutions containing urease, urease and (GES)/sub 2/, and ureaseSEG in 0.047M sodium phosphate buffer at pH 7.5 were given doses up to 750,000 r with Co/ sup 60/ gamma rays. The specific viscosity of urease decreases and then levels off at about three-fourths the original value. The viscosity in the urease solutions containing (GES)/sub 2/ did not decrease as nruch as the urease-SEG solutions after irradiation. The enzymatic activity is partially restored by gamma irradiation. Irradiation of solutions of urease containing (GES)/sub 2/ results in complete destruction of enzymatic activity. The viscosity in irradiated urease solutions are interpreted as indicating intramolecular rearrangement. (H.H.D.)
Research Organization:
Albert Einstein Medical Center, Philadelphia
NSA Number:
NSA-16-032781
OSTI ID:
4770778
Journal Information:
J. Albert Einstein Med. Center, Journal Name: J. Albert Einstein Med. Center Vol. Vol: 10
Country of Publication:
Country unknown/Code not available
Language:
English

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