RELATIONSHIP BETWEEN ACTIVITY OF FIBRINOGENASE AND INCREASED FIBRINOGEN CONTENT IN DOGS WITH RADIATION SICKNESS
Experiments were conducted on dogs to study the activity of fibrinogenase (in citrated blood plasma of test dogs) in acute radiation sickness accompanied by bleeding. After exposure, the period required for fibrinolysis usually increased, indicating a decrease in the activity of fibrinogenase. An increase in the fibrinogen content in the blood plasma of dogs wtih severe radiation sickness was a regular occurrence, taking place earlier in dogs with a pronounced hemorrhagic syndrome. No correlation was found between the changes in the fibrinogen content in the irradiated dogs and the changes in fibrinogenase activity. The coincidence of the increased fibrinogen content with the development of hemorrhage leads to the assumption that it is a reaction of the latter. (OTS)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-17-014098
- OSTI ID:
- 4734599
- Journal Information:
- Byul. Eksperim. Biol. i Med., Vol. Vol: No. 11; Other Information: Orig. Receipt Date: 31-DEC-63
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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