CONNECTION BETWEEN THE INCREASED FIBRINOGEN CONCENTRATION IN DOGS WITH RADIATION SICKNESS AND THE FIBRINOGENASE ACTIVITY

Journal Article · Fri Nov 01 04:00:00 EST 1963 · Bull. Exptl. Biol. Med. (U.S.S.R.) (English Transl.)

DOI:https://doi.org/10.1007/BF00785591· OSTI ID:4132720

Gordeeva, K V

A study was made of the concentration of blood plasma fibrinogen in relation to the changes of fibrinogenase activity. Dogs with radiation sickness (severe, moderately severe, and mild) served as experimental animals. A rise of the blood plasma fibrinogen content was observed in dogs with severe and moderately severe radiation sickness. This phenomenon is especially pronounced at the height of radiation sickness. The activity of fibrinogenase in severe radiation sickness was considerably decreased at the initial period and at the height of the disease. The rise of fibrinogen content in severe and moderately severe radiation sickness should be regarded as an adaptive reaction directed to control hemorrhages, not as the sequence of raduced fibrinogenase activity. (auth)

• Research Organization: Kirov Military Medical Academy, Leningrad
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-008143
• OSTI ID: 4132720
• Journal Information: Bull. Exptl. Biol. Med. (U.S.S.R.) (English Transl.), Journal Name: Bull. Exptl. Biol. Med. (U.S.S.R.) (English Transl.) Vol. Vol: 54
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BLOOD PLASMA
COAGULATION
DOGS
ENZYMES
FIBRINOGEN
HEMORRHAGE
PROTEINS
QUANTITY RATIO
RADIATION SICKNESS
VARIATIONS