ANTHRAX IMMUNITY UPON THE ACTION OF IONIZING RADIATION ON THE ORGANISM

Journal Article · Mon Jan 01 04:00:00 EST 1962 · Zh. Mikrobiol., Epidemiol. i Immunobiol.

OSTI ID:4720234

Silant'ev, E I; Ankudinov, V A; Kolesov, S G

The possibility of developing a specific immunity to anthrax in animals irradiated before and after inoculation with live anthrax vaccine was investigated. In two groups of guinea pigs the relation between the anthrax immunity and a mild form of radiation sickness was studied. Three out of 22 animals irradiated prior to immunization perished. None of the animals irradiated after immunization died. Radiation doses that caused a relatively mild form of radiation sickness had no effect on the formation of a specific anthrax immunity and do not change the animal's resistance to this infection after vaccination, provided that the interval between immunization and irradiation was not less than 9 to 10 days. Animals immunized before irradiation with low doses retained their specific anthrax immunity. Two to three weeks after the exposure of nonimmunized animals to the same radiation doses a stable anthrax immunity developed after inoculation with vaccine. (OTS)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-17-019880
• OSTI ID: 4720234
• Journal Information: Zh. Mikrobiol., Epidemiol. i Immunobiol., Journal Name: Zh. Mikrobiol., Epidemiol. i Immunobiol. Vol. Vol: No. 11
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
GUINEA PIGS
IMMUNITY
INFECTIONS
RADIATION DOSES
RADIATION EFFECTS
RADIATION SICKNESS
VACCINES