THE INFLUENCE OF PRELIMINARY VACCINATION WITH LIVE ANTIPLAGUE EB VACCINE ON THE RADIORESISTANCE OF ANIMALS

Journal Article · Fri Mar 01 04:00:00 EST 1963 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4699886

Smirnova, O V

Experiments were carried out on albino mice, guinea pigs, and rabbits involving preliminary introduction of different doses of live antiplague EB vaccine before lethal and sublethal irradiation. The live antiplague EB vaccine exerted an aggravating effect on the course of radiation sickness in albino mice and rabbits. The administration of large doses of the ED vaccine prior to irradiation increases the lethality of animals and shortens the average life expectation. Such an effect of the EB vaccine on the radioresistance of animals is due, apparently, to the presence of residual toxicity of the EB strain. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-17-019865
• OSTI ID: 4699886
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 8: No. 3; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

BIOLOGY AND MEDICINE
GUINEA PIGS
IMMUNITY
IRRADIATION
LETHAL DOSE
MICE
RABBITS
RADIATION DOSES
RADIATION SICKNESS
SURVIVAL TIME
TOXICITY