DEPENDENCE OF THE REACTION OF THE BLOOD SYSTEM OF DOGS ON THE ORIGINAL STATE OF THE BLOOD-FORMING ELEMENTS IN CHRONIC Sr$sup 90$ IRRADIATION

Journal Article · Tue Jan 01 04:00:00 EST 1963 · Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.)

OSTI ID:4694654

Aleksandrova, M F; Selivanova, L N

Seven male dogs were fed Sr/sup 90/ in equilibrium with Y/sup 90/, 0.001 mu curie/g, for 320 days, with a tissue dose of 1.0-1.7 rad/day, totaling 400 rads. The dogs were divided into two groups, the bone marrow cells, erythroblasts and granulocytes being initially 1.5- to 2-fold higher in group two than in group one. The reaction of the two groups differed greatly. In the low- functional activity group the erythroblast activity after l0 months was 137% of normal although the erythroblasts in the peripheral blood averaged 10% higher. Reticulocytes decreased. In the group having an initially higher erythroblast level, the level decreased to 50% in a month and to 37% of normal in 5 months. There was no change in the blood stream. In group one the bone marrow granulocytes were about the same or slightiy higher after 7 months and decreased to 35% after 10 months. Put in group two there was a decrease to 35% after 1 month, a short period of granulopoiesis (3 months), and then a depression. The platelet level showed a clear tendency to decrease the first month and was 50% after 10 months. There was no great difference in the peripheral blood platelet content in the two groups. (TTT)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-17-031930
• OSTI ID: 4694654
• Journal Information: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Journal Name: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.) Vol. Vol: 3; ISSN RADOA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

BIOLOGY AND MEDICINE