TREATMENT OF RADIATION SICKNESS COMPLICATED BY ACUTE BLOOD LOSS
Journal Article
·
· Vop. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr.
OSTI ID:4693620
ABS>An investigation was conducted of the effect of combined treatment with plasma substitutes, vitamin B/sub 6/, and chlortetracycline in animals subjected to x-irradiation and acute hemorrhage. Twenty four rabbits were irradiated with a dose of 800 r, and eight dogs with a dose of 700 r. The animals were then bled from the femoral artery so as to bring about a blood loss to the extent of 40 to 60% of the total blood volume. Immediately afterwards the plasma substitutes polyglucin and ArmIPK were injected intravenously in a volume equal to that of the blood removed. Chlortetracycline was given in the food in a dose of 25,000 units (rabbits) or 100,000 units (dogs) twice daily for 2 to 3 weeks. Vitamin B/sub 6/ was given in a dose of 0.2 ml of 1% solution until the red blood count returned to normal. The plasma substitutes were effective in reversing shock, and 17 rabbits and 6 dogs survived the acute effects of the blood loss. Twelve rabbits and 1 dog survived the subsequently developing acute radiation sickness for a period of 3 months or longer. Six female rabbits which survived were mated, and 2 subsequently became pregnant and gave birth to normal litters. (OTS)
- Research Organization:
- Radiobiological Section, Academy of Sciences, Armenain SSR
- NSA Number:
- NSA-17-030448
- OSTI ID:
- 4693620
- Journal Information:
- Vop. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr., Journal Name: Vop. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr. Vol. Vol: 1
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
THE EFFICACY OF BLOOD SUBSTITUTION WITH POLYGLUCINE IN EXPERIMENTAL TREATMENT OF RADIATION SICKNESS
COMPLEX TREATMENT OF RADIATION SICKNESS IN BLOOD LOSS
Possibilities of treating acute radiation sickness
Journal Article
·
Wed Jul 01 00:00:00 EDT 1959
· Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR
·
OSTI ID:4242803
COMPLEX TREATMENT OF RADIATION SICKNESS IN BLOOD LOSS
Journal Article
·
Fri May 01 00:00:00 EDT 1959
· Vestnik Rentgenol. i Radiol.
·
OSTI ID:4241365
Possibilities of treating acute radiation sickness
Journal Article
·
Sun Dec 31 23:00:00 EST 1972
· Vet. Sb., v. 71, no. 3, pp. 33-37
·
OSTI ID:4436319