THE COURSE OF THE MORPHOLOGICAL AND CERTAIN HISTOCHEMICAL CHANGES IN THE SPLEEN AND LYMPH NODES AFTER GENERAL X-IRRADIATION

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Vop. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr.

OSTI ID:4686623

Pulatova, E E

The presence of ribonucleic and deoxyribonucleic acid, inorganic and organic iron was determined by appropriate histochemical methods in preparations of the lymph nodes and spleen of white mice removed at intervals up to 72 hours after subjection to a lethal dose (800 r) of x-irradiation. In the spleen, pyknosis of the nuclei of the lymphocytes was observed one hour after irradiation; after 3 hours the confines of the Malpighian bodies became indistinct and the lymphocytes in the centers were mainly destroyed. Accumulations of inorganic iron appeared at the same time in the reticular cells. After 12 hours nearly all the lymphocytes were destroyed, and many macrophages containing fragments of cells were present; plasma cells rich in ribonucleic acid were accumulating around the central arteries. The accumulation of inorganic iron continued up to 48 hours. Similar changes were noted in the lymphocytes and other cellular elements of the peritoneal lymph nodes. (OTS)

• Research Organization: Radiobiological Section, Academy of Sciences, Armenian SSR
• NSA Number: NSA-17-030383
• OSTI ID: 4686623
• Journal Information: Vop. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr., Journal Name: Vop. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr. Vol. Vol: 1
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ANIMAL CELLS
ARTERIES
BIOLOGY AND MEDICINE
BLOOD VESSELS
CYTOLOGY
DNA
INTESTINE
IRON COMPOUNDS
LETHAL DOSE
LYMPH SYSTEM
LYMPHOCYTES
MACROPHAGES
MICE
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PERITONEUM
PLASMA CELLS
QUALITATIVE ANALYSIS
QUANTITATIVE ANALYSIS
QUANTITY RATIO
RADIATION EFFECTS
RETICULAR CELLS
RIBONUCLEIC ACID
SPLEEN
VARIATIONS
X RADIATION