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MORPHOLOGICAL AND HISTOCHEMICAL CHANGES IN THE SPLEEN AND LYMPH NODE OF WHITE MICE IN RESPONSE TO RADIATION AND ANTIGENIC EFFECTS (in Russian)

Journal Article · · Vopr. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr.
OSTI ID:4022617
Research was carried out on 90 white ntice subjected to x irradiation (Series I), vaccination with a brucellosis vaccine (Series II), and to a combined action of these factors (Series III and IV). The spleen and lymph nodes were studied both morphologically and histochemically. When exposing the mice to a total x-ray dose of 335 r, visible destructive changes and the lowering of desoxyribonucleic and ribonucleic acid level were found to occur in the spleen and lymph nodes. In the case of a single vaccination of the mice with the brucellosis vaccine, a certain vaccinal hyperplasia was observed in the spleen and lymph nodes, the level of desoxyribonucleic and ribonucleic acid being normal. In vaccinating the white mice, following total irradiation, destructive changes along with a gradual lowering of desoxyribonucleic and ribonucleic acid level are observed in the spleen and lymph nodes. The total x irradiation following a singie vaccination with the brucellosis vaccine, brings about slight destructive changes along with a simultaneous reticular hyperplasia in the spleen and lymph nodes. The levels of desoxyribonucleic and ribonucleic acids are high at all times. (auth)
Research Organization:
Originating Research Org. not identified
NSA Number:
NSA-18-019740
OSTI ID:
4022617
Journal Information:
Vopr. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr., Journal Name: Vopr. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr. Vol. Vol: 2
Country of Publication:
Country unknown/Code not available
Language:
Russian

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Related Subjects

ANTIGENS
BACTERIA
BIOLOGY AND MEDICINE
BRUCELLA
CYTOLOGY
DNA
IMMUNITY
IRRADIATION
LYMPH NODES
LYMPH SYSTEM
METABOLISM
MICE
NUCLEIC ACIDS
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RIBONUCLEIC ACID
SPLEEN
TISSUES
VACCINATION
VARIATIONS
X RADIATION