THE HISTOCHEMICAL EFFECTS OF X-IRRADIATION UPON SPLEEN AND LYMPH NODES
Journal Article
·
· Sci. Sinica (Peking)
OSTI ID:4136448
The spleens and cervical lymph nodes from mice exposed to a single dose of 500to 800 r x radiation were removed at periods varying from one hour to forty- five days post-irradiation. The tissues were analyzed for nucleic acids, acid and sllutline phosphatase activity, glycogen content, and sulfhydryl groups. The nucleic acids contert began to drop 8 hours after irradiation, the acid phosphatase activity increased markedly after irradiation, the alkaline phosphatase activity increased slightly after irradiation. The sulfhydryl groups decreased immediately after irradiation, mainly owing to the change of erythrocytes in the spleen. There was no change in sulfhydryl content of the lymph nodes. The immediate and marked decrease of sulfhydryl groups in spleen is attributed to a series of processes including the ionization of water molecules in the tissue into oxidizing agents. The degree and duration of the histochemical changes were in proportion to the x radiation dosage used. 51 references. (C.H.)
- Research Organization:
- Inst. of Experimental Medicine, Chinese Academy of Medical Sciences, Peking
- NSA Number:
- NSA-14-016572
- OSTI ID:
- 4136448
- Journal Information:
- Sci. Sinica (Peking), Journal Name: Sci. Sinica (Peking) Vol. Vol: 9
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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