THE EFFECT OF VARIOUS TYPES AND DOSES OF IRRADIATION ON THE CATALASE AND PEROXIDASE ACTIVITY OF THE BLOOD OF RABBITS
The medical literature refers to the liver catalase activity following x- ray irradiation of rats but the data have not been related to the severity of the radiation sickness. Sixty-seven rabbits weighing 2.0 to 2.7 kg were irradiated with 400, 600, and 1200 rads from a PYM-3 (RUM) unit, at 12 r/min. The equivalent internal doses administered orally as a dibasic salt solution of P/sup 32/ were 1.2, 1.88, and 3.8 mu curies/g, respectively. A combined irradiation was performed by administration of P/sup 32/ immediately after external irradiation with half the dose. Catalase was determined manganometrically, and peroxidase with pyrogallol. The catalase activity in the blood decreased independently of the irradiation dose. Peroxidase turned out to be more resistant to irradiation, and its activity decreased only after a dose of 1200 rads. Internal irradiation affected the enzymes more severely than external irradiation. The determination of catalase activity together with examination of WBC may be of prognostic value if performed soon after irradiation as well as after the acute stage of radiation sickness. (OTS)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-17-030430
- OSTI ID:
- 4685913
- Journal Information:
- Soobshch. Akad. Nauk Gruz., Journal Name: Soobshch. Akad. Nauk Gruz. Vol. Vol: 28
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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Related Subjects
ANISOTROPY
ARGON
ATOMS
BIOLOGY AND MEDICINE
BLOOD
CATALASE
COLLISIONS
COPPER
DIAGNOSIS
DIAGRAMS
ELECTRONS
EMISSION
ENERGY
ENERGY RANGE
ENZYMES
HYDROXIDES
INTERACTIONS
INTESTINE
IONS
LATTICES
LAYERS
LEUCOCYTES
LIVER
MANGANESE OXIDES
MEASURED VALUES
MONOCRYSTALS
NUMERICALS
PEROXIDASES
PHENOLS
PHOSPHORUS 32
PLASMA
PYROGALLOL
QUALITATIVE ANALYSIS
RABBITS
RADIATION DOSES
RADIATION EFFECTS
RADIATION SICKNESS
RADIATION SOURCES
RATS
ROTATION
SALTS
SOLUTIONS
SPUTTERING
SURFACES
VARIATIONS
WEIGHT
X RADIATION