MODIFICATION OF THE GROWTH OF EHRLICH ASCITES TUMORS IN MICE BY NATURAL AND ULTRAVIOLET-IRRADIATED HETEROLOGOUS DESOXYRIBONUCLEIC ACID

Journal Article · Mon Jul 01 04:00:00 EDT 1963 · Zeitschrift fuer Naturforschung (West Germany) Divided into Z. Nautrforsch., A, and Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,

OSTI ID:4644615

Zahn, R K; Tiesler, E

Desoxyribonuclease activity in the serum of Ehrlich ascites was determined by viscosimetry to be equivalent to 2.3 plus or minus 0.7 x 10/sup - 6/ g/ml of crystalline beef pancreas desoxyribonuclease. Injections of heterologous DNA into the Ehrlich ascites tumor under specified conditions does not alter tumor development. After uv irradiation, however, the DNA becomes strongly inhibitory for tumor growth. The possible implications are discussed. (auth)

• Research Organization: Universitat, Frankfurt am Main
• NSA Number: NSA-17-035588
• OSTI ID: 4644615
• Journal Information: Zeitschrift fuer Naturforschung (West Germany) Divided into Z. Nautrforsch., A, and Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,, Journal Name: Zeitschrift fuer Naturforschung (West Germany) Divided into Z. Nautrforsch., A, and Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys., Vol. Vol: 18b; ISSN ZNTFA
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

ANIMALS
BIOLOGY AND MEDICINE
BLOOD SERUM
DNA
EHRLICH ASCITES
ENZYMES
GLANDS
MEASURED VALUES
MEAT
MICE
MITOSIS
NUCLEIC ACIDS
PANCREAS
RADIATION EFFECTS
TUMORS
ULTRAVIOLET RADIATION
VISCOSITY