EFFECTS OF *beta/-AMINOETHYLISOTHIOUREA (AET) ON MUTATIONS INDUCED IN MICE BY X RAYS. II. DECREASE OF THE RATE OF DOMINANT LETHALITY INDUCED IN SPERMATOZOIDS IRRADIATED WITH HIGH DOSES OF X RAys

Journal Article · Tue Jan 01 04:00:00 EST 1963 · Compt. Rend. Soc. Biol.

OSTI ID:4618421

Leonard, A; Maisin, J R

ABS>In a preceding study it was shown that the dibromohydrate of AET, injected intraperitoneally, does not increase the number of spontaneous lethals of non-irradiated mouse spermatozoids and does not decrease the number of dominant lethal mutants induced by irradiation of mouse spermatozoids with 400 r of x rays. The study was extended to x-ray doses of 1200 r. The results show that although AET reduces the lethal mutants induced in spermatozoids, the degree of protection offered by this product is, however, much less than that offered to other radiosensitive organs as the intestine. The protection is also less than that given by cysteamine. (J.S.R.)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-17-040667
• OSTI ID: 4618421
• Journal Information: Compt. Rend. Soc. Biol., Journal Name: Compt. Rend. Soc. Biol. Vol. Vol: 157
• Country of Publication: Country unknown/Code not available
• Language: French

Related Subjects

AET
ANIMAL CELLS
BIOLOGY AND MEDICINE
CYSTEAMINE
GONADS
INTESTINE
IRRADIATION
MICE
MUTATIONS
ORGANIC SULFUR COMPOUNDS
RADIATION DOSES
RADIATION EFFECTS
RADIATION PROTECTION
RADIOSENSITIVITY
TISSUES
X RADIATION