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Determination of nitric oxide in blood by isotope dilution analysis

Conference ·
OSTI ID:4426155

From 1st international conference on stable isotopes in chemistry, biology, and medicine; Argonne, Illinois, USA (9 May 1973). In proceedings of the first international conference on stable isotopes in chemistry, biology, and medicine. Isotope dilution analysis using field ionization mass spectrometry was used for the determination of nitric oxide in blood. Blood exposed to a known amount of /sup 15/NO exchanges any bound /sup 14/NO with excess /sup 15/NO, resulting in an isotopic dilution of the latter. The precision of the method stands at +10%, which seems acceptable for epidemiological or physiological investigations. (JGB)

Research Organization:
Stanford Research Inst., Menlo Park, CA; Argonne National Lab., Ill. (USA)
NSA Number:
NSA-29-000038
OSTI ID:
4426155
Report Number(s):
CONF-730525--
Country of Publication:
Country unknown/Code not available
Language:
English