THE EFFECT OF X-IRRADIATION ON PREFORMED ANTIBODY AND ITS ROLE IN THE PROTECTION OF X-IRRADIATED MICE
Technical Report
·
OSTI ID:4341552
Induced agglutinin titers for human type A erythrocytes were not decreased by exposure to 300, 500, or 700 r of total-body x irradiation 3, 7, 11, or 15 days following radiation exposure in albino rats. Antibody derived from mice exposed to x irradiation did not lose capacity to effectively protect against infection. Passive immunization of normal (nonirradiated) or 300 or 400 r x-irradiated animals proved just as effective a measure for protection as did active immunization. At higher levels antibody (passive immunization) afforded no protection. The possible roles of antibody and cells in the irradiated animal are discussed. (auth)
- Research Organization:
- Utah. Univ., Salt Lake City. Coll. of Medicine
- NSA Number:
- NSA-12-004671
- OSTI ID:
- 4341552
- Report Number(s):
- AF-SAM-58-18
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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