Variation with sex of irradiated-induced chromosome damage in somatic cells of Drosophila melanogaster

Journal Article · Fri Jan 18 04:00:00 EDT 1974 · Nature (London), v. 247, no. 5437, pp. 151-152

DOI:https://doi.org/10.1038/247151a0· OSTI ID:4335874

Gatti, M; Tanzarella, C; Olivieri, G

It is stated that although much information has been collected on chromosome mutations in Drosophila melanogaster, as analyzed by genetic methods, there has so far been no cytological analysis of the chromosome mutations induced in somatic cells. In the studies described cells were irradiated, in which it was known that somatic pairing was present, to verify earlier studies on the influence of chromosome pairing on the type and frequency of induced chromosome aberrations. Irradiation was with approximates 300 to 1250 R of x rays at 125 R/ min. The main types of chromosome and chromatid aberrations that could be scored are shown. It was found that in the females there was a greater frequency of aberrations of every type. It is difficult to determine the cause of this difference, but a difference in the efficiency of repair both of premutational damage and of broken chromosomes may be involved. There was almost a total absence of intra-exchanges, both at chromatid and chromosome level, and it is thought that this is one of the effects associated with chromosome pairing. (UK)

• Research Organization: Consiglio Nazionale delle Richerche, Rome
• NSA Number: NSA-29-024509
• OSTI ID: 4335874
• Journal Information: Nature (London), v. 247, no. 5437, pp. 151-152, Journal Name: Nature (London), v. 247, no. 5437, pp. 151-152; ISSN NATUA
• Country of Publication: United Kingdom
• Language: English

Related Subjects

*CHROMOSOMAL ABERRATIONS-- RADIOINDUCTION
*CHROMOSOMES-- BIOLOGICAL RADIATION EFFECTS
*SOMATIC CELLS-- CHROMOSOMAL ABERRATIONS
DROSOPHILA
KEV RANGE 100-1000
N48531* --Life Sciences--Radiation Effects on Animals-- Invertebrates--Basic Studies
SEX
X RADIATION