THE EFFECT OF CYSTEAMINE, A RADIOPROTECTOR, ON THE VARIATION OF THE HEPATIC GLYCOGEN OF THE RAT AFTER WHOLE-BODY IRRADIATION WITH A MORTAL DOSE (HISTOCHEMICAL INVESTIGATION)

Journal Article · Wed Jan 01 04:00:00 EST 1958 · Radiobiologica Latina

OSTI ID:4324623

Fumagalli, P; Malaspina, A

The behavlor of the glycogen content of the llver of rats treated with cysteamine (10 mg/lOO gr of body weight) and of rats totally irradiated with a lethal dose of x rays (8OO r) after the administration of a protectlve dose of cysteamine was studied. lt was demonstrated that cysteamine determines glycogenolysis which is particularly evident two hours after treatment. The glycogen content of the liver is restored to normal after 24 hours. In totally irradiated animals receiving a protective dose of cysteamine, in the first hours after irradiation a marked glycogenolysis takes place, followed by glycogeno- sythesis, well evldeut 24 hours after irradiation, which restores to normal the glycogen content of the liver. (auth)

• Research Organization: Univ. of Messina, Italy; Istituto Radiologico dell'Ospedale Maggiore, Navara, Italy
• NSA Number: NSA-13-001931
• OSTI ID: 4324623
• Journal Information: Radiobiologica Latina, Journal Name: Radiobiologica Latina Vol. Vol: 1
• Country of Publication: Country unknown/Code not available
• Language: Italian

Related Subjects

AMINES
AMINO ACIDS
BIOLOGY AND MEDICINE
BODY
CARBOHYDRATES
CYSTEAMINE
ETHYL RADICALS
GLYCOGEN
LIVER
MEA
METABOLISM
ORGANIC SULFUR COMPOUNDS
POLYSACCHARIDES
QUANTITY RATIO
RADIATION PROTECTION
RATS
X RADIATION