THE BEHAVIOR OF THE ALKALINE PHOSPHATASE ACTIVITY OF THE LIVER OF THE RAT WHOLE-BODY X IRRADIATED AND PROTECTED WITH CYSTEAMINE

Journal Article · Wed Jan 01 04:00:00 EST 1958 · Radiobiologica Latina

OSTI ID:4282031

Paolo, F; Adalberto, M

By means of Gomori's method for the demonstration of alkaline phosphatase, the behavior of the enzyane activity of the liver of rats treated with cysteamine and of rats totally irradiated with 800 r after the administration of a protective dose of cysteamine was studied. The alkaline phosphatase activity increased in the liver cells of rats treated with cysteamine and also in Kupffer cells, which were preseut in great number. The alkaline phosphatase activity of the liver cells of rats irradiated after the administration of a protective dose of cysteamine did not differ from that of controls. In the liver of these rats during the first hours after irradiation numerous endothellal cells were present giving an intene reaction. Later, as in rats treated only with cysteamine, numerous cells appear, simllar to Kupffer cells, whlch are remarkably blackened by the cobalt sulfide. (auth)

• Research Organization: Univ. of MEssina, Italy; Istituto Radiologico dell'Ospedale Maggiore, Novara, Italy
• NSA Number: NSA-13-001933
• OSTI ID: 4282031
• Journal Information: Radiobiologica Latina, Journal Name: Radiobiologica Latina Vol. Vol: 1
• Country of Publication: Country unknown/Code not available
• Language: Italian

Related Subjects

AMINES
AMINO ACIDS
ANIMAL CELLS
BIOLOGY AND MEDICINE
BODY
COBALT SULFIDES
CYSTEAMINE
CYTOLOGY
ENZYMES
KUPFFER CELLS
LIVER
MEA
METABOLISM
MICROSCOPY
ORGANIC SULFUR COMPOUNDS
PHOSPHATASES
QUANTITY RATIO
RADIATION DOSES
RADIATION PROTECTION
RATS
X RADIATION