INVESTIGATION ON THE ALKALINE PHOSPHATASE OF THE ADRENAL GLAND OF THE RAT EXPOSED TO WHOLE-BODY X RADIATION AND TREATED WITH CYSTEAMINE

Journal Article · Thu Jan 01 04:00:00 EST 1959 · Radiobiol. Latina

OSTI ID:4215701

Pasqualino, A; Nesci, E; Nuvolone, U

The effects of whole-body x radiation, cysteamine, and radiation after injection of cysteamine on the alkaline phosphatase in the adrenal gland of the rat were studied by the Glick-Gomori method. Under normal conditions alkaline phosphatase can be shown histochemically in the glomerular, external fascicular, and X zones of the cortex, but none can be seen in the medulla. Whole-body x radiation causes the disappearance of the alkaline phosphatase for several days, but after 168 hours a return of the enzyme activity of the outer layers of the cortex is noticed. Treatment with cysteamine causes an increase of alkaline phosphatase in all layers of the cortex and involving chiefly the adventitia of the capillaries. Treatment with cysteamine before irradiation prevents the decrease in the enzyme activity which occurs after irradiation of the non- protected animal. (tr-auth)

• Research Organization: Universita Messina, Italy; Ospedale Maggiore Novara, Italy
• NSA Number: NSA-14-001396
• OSTI ID: 4215701
• Journal Information: Radiobiol. Latina, Journal Name: Radiobiol. Latina Vol. Vol: 2
• Country of Publication: Country unknown/Code not available
• Language: Italian

Related Subjects

ADRENAL GLANDS
AMINES
BIOCHEMISTRY
BIOLOGY AND MEDICINE
BLOOD VESSELS
BODY
CYSTEAMINE
ENZYMES
PHOSPHATASES
RADIATION EFFECTS
RADIATION PROTECTION
RATS
TISSUES
X RADIATION