THE COURSE OF THE EXUDATIVE PHASE OF INFLAMMATION IN IRRADIATED ANIMALS

Journal Article · Sat Aug 01 04:00:00 EDT 1959 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4222050

Bagramyan, E R

An exudative inflammation was induced in female rats by the Selye method. The protein composition of the blood serum and the inflammatory exudate was studied electrophoretically. In the irradiated rats (400 r) a change in the character of the inflammatory exudate and inhibition of the exudative phase of inflammation were noticed. The blood serum disclosed a diminution of the albumin content, and an increase of alpha /sub 1/, alpha /sub 2/, and BETA globulins. During the course of inflammation the blood serum or irradiated and nonirradiated rats showed almost analogous changes: a drop of albumin fraction and a rise of alpha /sub 1/- alpha /sub 2/-, and -globulin fraction and a sification of the severity of radiation sickness. The gamma -globulin fraction showed a tendency to decrease in the blood serum of irradiated rats with inflammation. All protein fractions of the serum in normal and irradiated aats passed into the inflammatory exudate. The percentage content of albumins and BETA globulins in the exudate of nonirradiated rats was higher than in the serum, while that of alpha /sub 1/, alpha /sub 2/, and gamma globulins was lower. Changes in the percentage content of albumins and gamma globulins in the exudate of irradiated rats. as compared with their scrum. depended upon the severity of radiation sickness. ACTH inhibited the development of exudative inflammation and increased the death rate of irradiated animals. (auth)

• Research Organization: All-Union Inst. of Experimental Endocrinology
• NSA Number: NSA-13-020828
• OSTI ID: 4222050
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 8; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ACTH
ADRENAL GLANDS
ALBUMINS
BIOCHEMISTRY
BIOLOGY AND MEDICINE
BLOOD PLASMA
BLOOD SERUM
DISEASES
ELECTROPHORESIS
GLOBULINS
HORMONES
IRRADIATION
LETHAL DOSE
NERVOUS SYSTEM
PHYSIOLOGY
PROTEINS
QUALITATIVE ANALYSIS
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RADIATION SICKNESS
RATS
SEX
STANDARDS
STATISTICS
SURVIVAL TIME
TISSUES
VARIATIONS