THE EFFECT OF GENERAL X-RAYS IRRADIATION ON THE RESTORATION OF SERUM PROTEINS IN DOGS AFTER HEMORRHAGE

Journal Article · Mon Sep 01 04:00:00 EDT 1958 · Voprosy Med. Khim.

OSTI ID:4201445

Rodionov, V M; Uspenskaya, V D; Zamyatkina, O G; Grunt, T A; Polyakova, V P

The aim of this research was to study the shifts in the normal restoration picture of various fractions of serum proteins after hemorrhage following irradiation. Various tables and diagrams and electrophoretic tracings accompany the article. The authors make the following conclusions: the majority of dogs in which hemorrhage was induced 1-6 days after irradiation (by 500 r) died. In these dogs, essential changes were noted in the processes of serum protein restoration, and there was an increase in the blood stream of a type of protein having the electrophoretic mobility of alpha globulins. In dogs subjected to hemorrhage 1 1/2 months after irradiation, the serum protein restoration picture was similar to that of nonirradiated animals subjected to hemorrhage. Evidently these facts indicate that during the acute phase of radiation sickness the processes of regeneration of serum albumin are inhibited, but the organism does not lose the capacity to mobilize extravascular reserves of this protein and to use alpha-3globulin sources as the albumin deficiency rises in the vascular bed.

• Research Organization: Academy of Medical Sciences, U.S.S.R.
• NSA Number: NSA-13-020860
• OSTI ID: 4201445
• Journal Information: Voprosy Med. Khim., Journal Name: Voprosy Med. Khim. Vol. Vol: 4
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ALBUMINS
BIOLOGY AND MEDICINE
BLOOD
BLOOD SERUM
BODY
DIAGRAMS
DOGS
ELECTROPHORESIS
GLOBULINS
HEMORRHAGE
IRRADIATION
LETHAL DOSE
PRODUCTION
PROTEINS
RADIATION DOSES
RADIATION EFFECTS
RADIATION SICKNESS
RECOVERY
REGENERATION
STANDARDS
SURVIVAL TIME
TABLES
TESTING
VARIATIONS
X RADIATION