MORPHOLOGICAL AND HISTOCHEMICAL MODIFICATION OF EHRLICH ASCITES TUMORS FOLLOWING REPEATED IRRADIATION WITH X RAYS IN VIVO (in Italian)
The authors irradiated mice carrying the Ehrlich ascites tumor with750 r in fractionated doses and followed the changes in nucleic acids. Up to750 r they observed a decrease of RNA and an increase of DNA, and 96 hours after the last irradiation an inversion of this relation, with a pronounced increase of RNA and a great dinflnution of DNA. Considerable alterationa in the morphological distribution of the two acids were observed, and, after 300 r the pyronin- staining granules of the cytoplasm disappeared altogether. Further, they observed destruction of the reticular structure of the nucleus and fusion of the DNA into large masses which progressively joined up to form one single mass. (auth)
- Research Organization:
- Universita, Rome
- NSA Number:
- NSA-14-008375
- OSTI ID:
- 4196141
- Journal Information:
- Radiobiol. Latina, Journal Name: Radiobiol. Latina Vol. Vol: 2
- Country of Publication:
- Country unknown/Code not available
- Language:
- Italian
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