THE USE OF CALCIUM-47 IN DIAGNOSTIC STUDIES OF PATIENTS WITH BONE LESIONS

Technical Report · Thu Dec 31 23:00:00 EST 1959

OSTI ID:4181931

Corey, K R; Kenny, P; Greenberg, E; Pazianos, A; Pearson, O H; Laughlin, J S

Physical aspects of calcium-47 and problems of its production and assay are reviewed. Its energetic gamma spectrum and 4.7 day half-life make it very useful for calcium metabolic studies. Dosimetric considerations in both tracer and therapeutic applications are discussed. Results are reported from kinetic and external counting studies using tracer doses of calcium-47 in patients with a variety of bone lesions. The accretion rate and size of the exchangeable calcium pool were measured tn patients with breast carcinoma. The accretion rate was found to be elevated in patients whose bone metastases were clinically active. A whole-body scanner is described which was developed to improve and extend the clinical uses of calcium-47. (C.H.)

• Research Organization: Sloan-Kettering Inst. for Cancer Research , New York
• NSA Number: NSA-14-016499
• OSTI ID: 4181931
• Report Number(s): TID-5954
• Country of Publication: United States
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BODY
BONES
CALCIUM 47
CANCER
COUNTERS
DIAGNOSIS
DISEASES
DOSEMETERS
GAMMA RADIATION
GLANDS
HALF-LIFE
MAMMARY GLANDS
MAN
MEDICINE
METABOLISM
METASTASES
PLANNING
PRODUCTION
QUANTITATIVE ANALYSIS
RADIOTHERAPY
SPECTRA
TRACE AMOUNTS
TRACER TECHNIQUES
USES