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RADIOPROTECTION OF FEMALE RATS WITH AET

Technical Report ·
OSTI ID:4179060

The protective effect of S,2-aminoethylisothiuronium dibromide (AET) against the injury caused by gamma rays was studied in the female rat. Significant protection was achieved using either intraperitoneal injection or gavage. The drug was somewhat more effective when given by the parenteral rather than by the oral route. It was also noted that as the dose rate was decreased from approximately 1,000 to 500 to 100 r per minute, the protective effect of oral treatment with AET was also decreased. Further evidence suggests that larger animals are more susceptible to the toxic effects of the protective drug itself. (auth)

Research Organization:
School of Aviation Medicine, Brooks AFB, Tex.; Texas. Univ., Austin. Radiobiological Lab.
NSA Number:
NSA-14-017689
OSTI ID:
4179060
Report Number(s):
AF-SAM-60-40
Country of Publication:
Country unknown/Code not available
Language:
English

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