POTENTIATION BY PENTOBARBITAL OF THE PROTECTIVE EFFECT OF AET AGAINST GAMMA RAYS
Technical Report
·
OSTI ID:4822699
Issued by School of Aerospace Medicine, Brooks AFB, Tex. Female rats were treated with the radioprotective drug S,beta-aminoethylisothiuronium dibromide (AET) in combination with pentobarbital sodium and irradiated with various dosages of gamma rays. This treatment appears to depend less on dose rate of radiation than does AET given alone; it also reduces the amount of AET which must be used to achieve a given degree of protection. The combination is more effective than either compound given singly. The results of this study support further the hypothesis that chemical agents with different modes of action may be successfully combined to achieve better radioprotection. (auth)
- Research Organization:
- Texas. Univ., Austin. Radiobiological Lab.
- NSA Number:
- NSA-16-005219
- OSTI ID:
- 4822699
- Report Number(s):
- AF-SAM-61-87
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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